产品描述
AIF是一种易位到细胞核诱导凋亡的线粒体蛋白, AIF可引起DNA破碎、染色质凝聚,还可诱导细胞色素C和Caspase-9从线粒体中释放出来,AIF从线粒体中的释放可被过度表达的Bcl-2(一种参与线粒体渗透的蛋白质)所抑制
相关标记:Alexa Fluor 350 Alexa Fluor 488
Alexa Fluor 555 Alexa Fluor 647
AP APC Biotin Cy3 Cy5 Cy5.5
Cy7 FITC Gold HRP PE PE-Cy3
PE-CY5 PE-CY5.5 PE-CY7 RBITC
英文名称:Anti-AIF
中文名称:调亡诱导因子抗体
Harlequin; Hq; mAIF; MGC111425; MGC5706; PDCD 8
PDCD8Programmed cell death 8; Programmed cell death 8 isoform 1
Programmed cell death 8 isoform 2; Programmed cell death 8 isoform 3
Programmed cell death protein 8 mitochondrial
Programmed cell death protein 8 mitochondrial precursor; Striatal apoptosis inducing factor
技术参数
浓度:1mg/1ml
抗体来源:Mouse
克隆类型:polyclonal
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep
产品类型:一抗
蛋白分子量:predicted molecular weight 57kDa
性状:Lyophilized or Liquid
免疫原:KLH conjugated synthetic peptide derived from human AIF N-terminus
亚型:IgG
纯化方法:affinity purified by Protein A
储存液:0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
产品应用:WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500
IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
The lyophilized antibody is stable at room temperature for at least one month
and for greater than a year when kept at -20°C.
When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable
for at least two weeks at 2-4 °C.
Important Note:This product as supplied is intended for research use only
not for use in human, therapeutic or diagnostic applications.