产品描述
AIF是一种易位到细胞核诱导凋亡的线粒体蛋白, AIF可引起DNA破碎、染色质凝聚,还可诱导细胞色素C和Caspase-9从线粒体中释放出来,AIF从线粒体中的释放可被过度表达的Bcl-2(一种参与线粒体渗透的蛋白质)所抑制
相关标记:Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555
Alexa Fluor 647 AP APC Biotin Cy3 Cy5 Cy5.5
Cy7 FITC Gold HRP PE PE-Cy3 PE-CY5
PE-CY5.5 PE-CY7 RBITC
英文名称:Anti-AIF
中文名称:调亡诱导因子抗体
别名:Apoptosis inducing factor; Harlequin; Hq; mAIF
MGC111425; MGC5706; PDCD 8; PDCD8; Programmed cell death 8
Programmed cell death 8 isoform 1; Programmed cell death 8 isoform 2
Programmed cell death 8 isoform 3; Programmed cell death protein 8 mitochondrial
Programmed cell death protein 8 mitochondrial precursor; Striatal apoptosis inducing factor
技术参数
浓度:1mg/1ml
抗体来源:Rabbit
克隆类型:polyclonal
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep,
产品类型:一抗
研究领域:细胞生物 染色质和核信号 神经生物学 细胞凋亡 细胞周期蛋白 线粒体
蛋白分子量:predicted molecular weight: 57kDa
性状:Lyophilized or Liquid
免疫原:KLH conjugated synthetic peptide derived from human AIF N-terminus
亚型:IgG
纯化方法:affinity purified by Protein A
储存液:0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
产品应用:WB=1:100-500 ELISA=1:500-1000
IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500
IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications
optimal dilutions/concentrations should be determined by the end user
保存条件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
The lyophilized antibody is stable at room temperature for at least one month
and for greater than a year when kept at -20°C
When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody
the antibody is stable for at least two weeks at 2-4 °C
Important Note:This product as supplied is intended for research use only
not for use in human, therapeutic or diagnostic applications